No. There is no way (that is said in the documentation) to do so. But what you can do is in newer versions that you install with NSIS is add the following code:
Section "Newer Version"
SectionIn
SetOutPath $INSTDIR
Delete "$PROGRAMFILES\myprogram1\MyProgram0101.exe"
Delete "$PROGRAMFILES\myprogram1\uninst-myprogram.exe"
File MyProgram1010.exe
For example.
Or you could just run the uninstaller before installing a new version, but that would leave more responsibility on the installer. Or just overwrite with the new program by adding the tag:
SetOverWrite ifnewer
Hope that helps,
Duane Jeffers
Developer; On-Demand Audio